Flotillin complex

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August undefined, 2024

WebCadherin-1 or Epithelial cadherin (E-cadherin), (not to be confused with the APC/C activator protein CDH1) is a protein that in humans is encoded by the CDH1 gene. Mutations are correlated with gastric, breast, colorectal, thyroid, and ovarian cancers.CDH1 has also been designated as CD324 (cluster of differentiation 324). It is a tumor suppressor gene. WebWikipedia

The roles of flotillin microdomains – endocytosis and …

WebDec 7, 2011 · They demonstrated that flotillin-1 forms a ternary complex with c-Cbl-associated protein (CAP) and the E3 ubiquitin protein ligase Cbl upon insulin stimulation (Figure 5). This was shown to be important for lipid raft association, downstream signaling of the CAP-Cbl complex and finally for glucose uptake by the glucose transporter GLUT4 … WebTwo flotillin members have been described, flotillin-1 and flotillin-2. In addition to its colocalization with lipid rafts on the plasma membrane, flotillin-1 also has been found in compartments of the endocytic and … cscbike mtb e-bike conversion kit

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WebPart of flotillin complex. Is active in glutamatergic synapse and presynaptic active zone membrane. Orthologous to human FLOT2 (flotillin 2); PARTICIPATES IN insulin signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8 … WebAbout. LakePoint Sports, the premier travel and youth sports destination in the country, serves athletes in more than 30 sports year-round, including baseball, basketball, volleyball, soccer, lacrosse, football, gymnastics … WebThe formation of the face in vertebrate animals is a complex and precisely orchestrated process involving the sequential migration, proliferation and … dysfunctional uterine bleeding postmenopausal

Flotillin 1 Polyclonal Antibody (PA5-19713) - Thermo Fisher Scientific

Anaplasma phagocytophilum Hijacks Flotillin and NPC1

WebMar 2, 2012 · We here show that flotillin-1 forms a complex with CRAF, MEK1, ERK, and KSR1 (kinase suppressor of RAS) and that flotillin-1 knockdown leads to a direct … WebNov 13, 2015 · My family was looking to go swimming that Friday, our last day, something simple, not a water park that costs $50pp. I did some research and came across Ft. … csc blank pdsWebJul 14, 2024 · Loss of flotillins leads to a decrease in membrane fluidity that in turn leads to alterations in MreB dynamics and, as a consequence, in peptidoglycan synthesis. These alterations are reverted when membrane fluidity is restored by a chemical fluidizer. In vitro, the addition of a flotillin increases membrane fluidity of liposomes. cscbluengold outlook.com

"Webcomplex subunit μ2; Flot, flotillin; Tnr, transferrin receptor. (B–E) Cholesterol-regulated recycling of flotillin-1 is depen-dent on NPC1L1. (B and C) Flotillin-1-RFP was … " - Flotillin complex

Flotillin complex

Research Brief: Flotillin, Cholesterol Aid APP Endocytosis

WebJun 15, 2024 · Here, we report for the first time about a 65-year-old woman presenting with a dementia combined with serum autoantibodies against flotillin-1/2 complex connected mainly to the plasma membrane … Webhetero-oligomeric complex that contains both caveolins 1 and 2. However, protein levels of flotillin-1 and flotillin-2/ESA remain unchanged in response to oncogenic …

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WebMay 28, 2024 · We then treated the cells with the cross-linker DSP and immunoprecipitated flotillin-1 with Flag antibody. Similar amounts of Flag signal and flotillin-2 were … WebOct 20, 2024 · d, e Interaction networks of the V-ATPase (d) and the flotillin (e) complex. f Co-IP of ATP6V1D and FZD9 (n = 2). ATP6V1B2 and ATP6V1A1 are known members of the V-ATPase complex; LAMP2 is a ...

WebERLIN2, also named as C8orf2 and SPFH2, is a component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1, 4, 5-trisphosphate receptors (IP3Rs) such as ITPR1. It promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin … WebJan 1, 2024 · Flotillin-2 was originally cloned in 1994 by Schroeder et al. by immunoscreening of a human keratinocyte cDNA library using the monoclonal antibody ECS-1 against cultured keratinocytes. ... palmitoylation, and hydrophobic interaction. Flotillin-2 is mainly found in a hetero-oligomeric complex with its homologue flotillin-1, …

WebDepletion of flotillin-1, flotillin-2 or both flotillins together by small interfering RNAs (siRNAs) did not inhibit PKC-dependent internalization and degradation of HA-DAT. In contrast, siRNAs to clathrin heavy chain and μ2 subunit of clathrin adaptor complex AP-2 as well as a dynamin inhibitor Dyngo-4A significantly decreased PKC-dependent ... WebFlotillin-mediated endocytosis and ALIX–syntenin-1–mediated exocytosis protect the cell membrane from damage caused by necroptosis Weiliang Fan1,2, ... for the cross-linking and tandem affinity purification of the lipid raft–bound phospho-MLKL protein complex. TSZ, TNF (20 ng/ml), Smac mimetic (100 M), and z-VAD (20 M); DSP, dithiobis ...

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• Schroeder WT, Stewart-Galetka S, Mandavilli S, et al. (1994). "Cloning and characterization of a novel epidermal cell surface antigen (ESA)". J. Biol. Chem. 269 (31): 19983–91. doi:10.1016/S0021-9258(17)32117-8. PMID 8051082. • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298. dysfunction in emotional awarenessWebSep 26, 2024 · Part of flotillin complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human FLOT1 (flotillin 1). [provided by Alliance of Genome Resources, Apr 2024] Other designations. flotillin-1. GeneRIFs: Gene References Into … dysfunction of right eustachian tubeWebMay 24, 2016 · Figure. 2C shows that the formation of flotillin-1 and flotillin-2 hetero-oligomers activates the sfGFP BiFC complex, as evidenced by the green fluorescent clusters seen on the cell membrane. The distribution pattern of flotillin-1 and flotillin-2 formed a BiFC complex comparable to previous biochemical assay results obtained by … csc bike reviewsWebJun 23, 2024 · Flotillin-1 and Flotillin-2 (synonyms: reggie-2 and reggie-1) were originally described to be upregulated in regenerating axons of goldfish retinal ganglion cells after … dysfunction of right eustachian tube icd 10WebA protein complex that contains flotillin-1 and flotillin-2, and may contain associated proteins. Flotillins associate into membrane microdomains resembling caveolae. Source: … dysfunctional uterine bleeding perimenopausehttp://biopioneer.com.tw/?p=41034 csc blythewood sc jobsWebJul 3, 2024 · Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are associated with obesity. They are accompanied by increased levels of free cholesterol in the liver. Most free cholesterol resides within the plasma membrane. We assessed the impact of adding or removing free cholesterol on the function and … csc bling